Betadine is an iodine-based antimicrobial available as an ointment, swab, tincture or skin cream. People generally use Betadine cream on minor scrapes and cuts to prevent infection. Medical professionals also use Betadine as a topical antiseptic before and during sterile surgical procedures. Like other iodine-based products, Betadine can stain the clothing. Spot away 1 quickly neutralizes betadine and iodine-based stains and spills. Effective removes betadine and iodine-based stains from hard surfaces. Versatile fabrics and linens in laundry applications.